Sunday February 17, 2008
Clostridium difficile-Associated Disease in the ICU Setting

Recently one retrospective observational, cohort study was performed to analyse 30-Day mortality for Clostridium difficile associated disease (CDAD) in the ICU Setting.

278 patients with CDAD admitted to an ICU were identified over a 2-year period.

• The overall 30-day mortality rate was 36.7% (n = 102), Independent predictors for 30-day mortality were septic shock, ward-to-ICU transfer and increasing APACHE II scores
• The attributable mortality associated with CDAD was estimated to be 6.1%
• CDAD was associated with an excess ICU length of stay (2.2 days)
• CDAD was associated with an excess hospital length of stay (4.5 days)
  
  

Editors' note: C.diff is well known to intensivists. Objective of above post is to reinforce the high suspicion towards C. diff.



References: click to get abstract/articles

1. Analysis of 30-Day Mortality for Clostridium difficile-Associated Disease in the ICU Setting - Chest. 2007; 132:418-424