Wednesday, February 13, 2008

Wednesday February 13, 2008

Q; Name few drugs which can be use in VRE (Vancomycin-resistant enterococcus) Meningitis ?


A;
New growing literature is showing that IV and even PO Zyvox (linezolid) should be the first line of treatment in VRE Meningitis as it has a very good penetration in CSF.

Other viable choices are chloramphenicol, Ampicillin (or penicillin) and Synercid (Quinupristin/dalfopristin).






Reference: click to get abstract/article

1.
Successful treatment of vancomycin-resistant enterococcus meningitis with linezolid: Case report and review of the literature Critical Care Medicine. 29(12):2383-2385, December 2001.